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5-Bromo-2-chloropyrimidine CAS#32779-36-5

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  • 5-Bromo-2-chloropyrimidine CAS#32779-36-5
  • 5-Bromo-2-chloropyrimidine CAS#32779-36-5
  • 5-Bromo-2-chloropyrimidine CAS#32779-36-5
  • 5-Bromo-2-chloropyrimidine CAS#32779-36-5
  • 5-Bromo-2-chloropyrimidine CAS#32779-36-5

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5-Bromo-2-chloropyrimidine CAS#32779-36-5
5-Bromo-2-chloropyrimidine CAS 32779-36-5 is a key pharmaceutical intermediate for macitentan synthesis and advanced drug development.

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Product Description

Valuable Pharmaceutical Intermediate: Widely used in the synthesis of macitentan, an endothelin receptor antagonist for pulmonary hypertension treatment.


Reactive Halogenated Structure: Contains both chloro and bromo substituents, enabling versatile chemical transformations and functionalization.


High Synthetic Utility: The pyrimidine core structure supports efficient incorporation into complex drug molecules.


Supports Advanced Drug Development: Facilitates the production of targeted therapeutic agents, making it important for modern pharmaceutical research.


Product Description of 5-Bromo-2-chloropyrimidine CAS#32779-36-5

5-Bromo-2-chloropyrimidine is a halogenated pyrimidine derivative featuring chloro and bromo substituents at the 2- and 5-positions of the ring. It is primarily used as a pharmaceutical intermediate in the synthesis of macitentan, an endothelin receptor antagonist employed in the treatment of pulmonary hypertension.


Product Applications of 5-Bromo-2-chloropyrimidine CAS#32779-36-5

5-Bromo-2-chloropyrimidine is used as a pharmaceutical intermediate in the synthesis of various drug compounds, including inhibitors. It is also utilized in cross-coupling reactions involving indium organometallic reagents with 2,5-dihalopyrimidines.


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